Trace amounts of microbe-killing molecules predict chronic granulomatous disease survival

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Trace amounts of microbe-killing molecules predict chronic granulomatous disease survival

sciencedaily.com

Investigators have observed that the survival rate of people with a rare immunodeficiency disease called chronic granulomatous disease (CGD) is greatly improved when even very low levels of microbe-killing molecules are present. Because production of these molecules, made by an enzyme called NADPH oxidase, can be predicted from genetic analysis, a patient's risk for severe CGD could be assessed very early in life, allowing for more personalized treatment, say the researchers.

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Tags: Genetic, Disease and Condition, disease

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