Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema : Nature Medicine : Nature Publishing Group
Links shared publicly online about this topic.
- 1,016total visits
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema : Nature Medicine : Nature Publishing Group
Rubin Tuder and his colleagues show that cigarette smoke induces expression of Rtp801 (also known as Redd1), a hypoxia-inducible protein that inhibits mTOR activity and enhances oxidative stress-mediated cell death. They also show that mice deficient in Rtp801 are protected from cigarette smoke-induced lung injury, thus suggesting the protein as a target to prevent emphysema.
View full resource at nature.com
Tags: Lung, COPD, Protein, Pulmonology, Emphysema
Most Recently Shared on July 17, 2010 at 12:00 pm By:
Research Library: Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulm... http://bit.ly/dkwQ5B
Advertisement
