Proteasome inhibitor reduces inflammation and promotes bone healing in arthritis models

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Proteasome inhibitor reduces inflammation and promotes bone healing in arthritis models

sciencedaily.com

A new study by Greek researchers suggests that the biologic drug bortezomib (Velcade), a proteasome inhibitor used to treat multiple myeloma (bone marrow cancer), may represent a promising treatment for rheumatoid arthritis (RA). In this study, bortezomib displayed favorable effects in an animal model of inflammatory arthritis that mimics RA, in reducing disease severity and inflammation, and promoting bone healing.

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Tags: Cancer, Multiple Myeloma, Bone, Arthritis, Rheumatoid Arthritis, Drug, Nature

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