Polyclonality of BRAF mutations in acquired melanocytic nevi
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Polyclonality of BRAF mutations in acquired melanocytic nevi
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Tags: Cancer
Most Recently Shared on September 15, 2009 at 1:17 am By:
Polyclonality of BRAF mutations in acquired melanocytic nevi http://bit.ly/PehjH
Molecular Nevogenesis
hindawi.com — “Despite recent advances, the biology underlying nevogenesis remains unclear. Activating mutations in NRAS, HRAS, BRAF, and GNAQ have been identified in benign nevi. Their presence roughly correlates with congenital, Spitz, acquired, and blue nevi, respectively. These mutations are likely to play a critical role in driving nevogenesis. While each mutation is able to activate the MAP kinase pathway, they also interact with a host of different proteins in other pathways. The different melanocytic d” View full resource at hindawi.com
Most Recently Shared on April 8, 2011 at 3:42 am By:
Molecular Nevogenesis: Despite recent advances, the biology underlying nevogenesis remains unclear. Activating m... http://bit.ly/ezF3Q1
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