Platelet responsiveness and stent thrombosis

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Platelet responsiveness and stent thrombosis

theheart.org

More evidence that patients who show a low platelet response to clopidogrel have an increased risk of stent thrombosis has been reported, with the suggestion that antiplatelet therapy should be intensified in this group. (Sibbing D et al. J Am Coll Cardiol 2009; 53:849-856.)

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Tags: Anti-Clotting Medication, Plavix, Iscover

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Most Recently Shared on March 6, 2009 at 10:33 pm By:

theheartorg Shelley Wood

More support for clopidogrel platelet response testing http://tinyurl.com/ccgtef

3 years ago...

Very Late Stent Thrombosis Approximately 7 Years After Deployment and One-Week Cessation of Dual Antiplatelet Therapy | Journal of Invasive Cardiology

invasivecardiology.com — “Very Late Stent Thrombosis Approximately 7 Years After Deployment and One-Week Cessation of Dual Antiplatelet Therapy | Journal of Invasive CardiologyView full resource at invasivecardiology.com

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Most Recently Shared on December 16, 2011 at 7:34 pm By:

InvasiveCardiol Invasive Cardiology Cardiology and Medical Journal

Longest reported interval. Stent thrombosis 7 yrs post DES deployment -- 1 week after dual anti-platelet therapy stops. http://t.co/NC9N2XwQ

4 months ago...

30-day results of ADAPT-DES registry reported at TCT 2011

medicalxpress.com — “The relationship of platelet responsiveness to antiplatelet medications; and, the correlation of poor response, and overall platelet aggregation while on dual antiplatelet therapy to the risk of drug-eluting stent thrombosis after 30 days was examined in ADAPT-DES, the largest registry to date to fully ...View full resource at medicalxpress.com

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Most Recently Shared on November 9, 2011 at 9:10 pm By:

physorg_health PhysOrg Health News Health News

30-day results of ADAPT-DES registry reported at TCT 2011 http://t.co/7p8RDOJy

6 months ago...

MedWire News - Thrombosis - Early stent thrombosis predictors identified

medwire-news.md — “MedWire News Variants in three genes associated with clopidogrel metabolism and platelet receptor function are independently associated with early stent thrombosis in patients undergoing percutaneous coronary intervention, study data show. MedWire NewsView full resource at medwire-news.md

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Most Recently Shared on October 27, 2011 at 9:25 am By:

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Early stent thrombosis predictors identified http://t.co/e1Dcb2dA

6 months ago...

More Data But No Answers About Platelet Function Testing - Forbes

forbes.com — “The RECLOSE 2–ACS (Responsiveness to Clopidogrel and Stent Thrombosis 2–ACS) trial from Italy provides new information about platelet reactivity but doesn't answer any of the key questions about the possible role of platelet function testing in clinical practice. In a paper published in JAMA, Guido Parodi and colleagues report on 1,789 ACS patients who underwent [...]View full resource at forbes.com

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Most Recently Shared on September 21, 2011 at 5:36 pm By:

Drugs_Devices Drugs and Devices OW OW Health

More Data But No Answers About Platelet Function Testing: The RECLOSE 2-ACS (Responsiveness to Clopidog... http://t.co/GhqQuk0I #drug

7 months ago...

Lower achieved platelet reactivity associated with better cardiovascular

medicalxpress.com — “Compared to patients who had persistently high platelet reactivity, those who achieved low platelet reactivity, according to the VerifyNow P2Y12 Test, had a reduced incidence of cardiovascular death, heart attack and stent thrombosis, as indicated by a clinical trial presented today at the ESC Congress ...View full resource at medicalxpress.com

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Most Recently Shared on August 30, 2011 at 3:34 pm By:

physorg_health PhysOrg Health News Health News

Lower achieved platelet reactivity associated with better cardiovascular http://t.co/WOBrksl

8 months ago...

Internal Medicine - Cardiology Article | Myocardial infarction

mdlinx.com — “Relationship between clopidogrel-induced platelet P2Y12 inhibition and stent thrombosis or myocardial infarction after percutaneous coronary intervention-A case-control studyView full resource at mdlinx.com

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Most Recently Shared on July 27, 2011 at 7:08 pm By:

Symposier - A serious look at GRAVITAS - Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety

symposier.com — “Uploaded and shared in Youtube by: theheartorg — Heartwire's Sue Hughes sits down with Dr Sunil Rao to talk about the clinical implications of the results and what they mean for the future of platelet-function testing. http://www.theheart.org/editorial-program/1159543.doView full resource at symposier.com

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Most Recently Shared on June 9, 2011 at 12:04 am By:

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A serious look at GRAVITAS - Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety. http://bit.ly/m5QZtK

11 months ago...

Study examines outcomes of high-dose antiplatelet drug after stent placement

physorg.com — “Modifying a patient's dosage of the antiplatelet drug clopidogrel for 6 months depending on the patient's level of platelet reactivity did not result in combined lower rates of nonfatal heart attack, stent thrombosis (clot) and cardiovascular death in patients who had a procedure such as balloon angioplasty ...View full resource at physorg.com

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Most Recently Shared on March 15, 2011 at 9:08 pm By:

physorg_health PhysOrg Health News Health News

Study examines outcomes of high-dose antiplatelet drug after stent placement http://tw.physorg.com/219427381

1 year ago...

Study Examines Outcomes of High-Dose Antiplatelet Drug After Stent Placement

newswise.com — “Modifying a patient--™s dosage of the antiplatelet drug clopidogrel for 6 months depending on the patient--™s level of platelet reactivity did not result in combined lower rates of nonfatal heart attack, stent thrombosis (clot) and cardiovascular death in patients who had a procedure such as balloon angioplasty and received a drug-releasing coronary stent, according to a study in the March 16 issue of JAMA.View full resource at newswise.com

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Most Recently Shared on March 15, 2011 at 8:23 pm By:

newswise newswise Health Communicator and Health News

Study Examines Outcomes of High-Dose Antiplatelet Drug After Stent Placement: Modifying a patient's dosage of th... http://bit.ly/hOcHHY

1 year ago...

Study Examines Outcomes of High-Dose Antiplatelet Drug After Stent Placement

newswise.com — “Modifying a patient--™s dosage of the antiplatelet drug clopidogrel for 6 months depending on the patient--™s level of platelet reactivity did not result in combined lower rates of nonfatal heart attack, stent thrombosis (clot) and cardiovascular death in patients who had a procedure such as balloon angioplasty and received a drug-releasing coronary stent, according to a study in the March 16 issue of JAMA.View full resource at newswise.com

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Most Recently Shared on March 15, 2011 at 8:21 pm By:

mednewswise Thom Canalichio Health News

#health news: Study Examines Outcomes of High-Dose Antiplatelet Drug After Stent Placement: Modifying a patient'... http://bit.ly/hmS7Qs

1 year ago...

GRAVITAS Trial finds high dose of clopidogrel does not reduce risk of ischemic events

news-medical.net — “Accumetrics, Inc., developer and marketer of the VerifyNow System, today announced that the GRAVITAS (Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety) Trial found that in patients with high residual platelet reactivity, doubling the maintenance dose of clopidogrel did not reduce the risk of further ischemic events after percutaneous coronary intervention (PCI).View full resource at news-medical.net

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Most Recently Shared on November 19, 2010 at 8:26 pm By:

Stroke_News News-Medical.Net Health News

Stroke News: GRAVITAS Trial finds high dose of clopidogrel does not reduce risk of ischemic events: Accumetric... http://twurl.nl/hydpwz

1 year ago...

Clopidogrel response and cardiac death | theheart.org

theheart.org — “A platelet-reactivity index of over 60% on the VASP test was associated with an increased rate of death and stent thrombosis. The deleterious impact of a low response to clopidogrel was significantly higher in patients who received a drug-eluting stent.View full resource at theheart.org

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Most Recently Shared on June 28, 2010 at 11:19 am By:

plateletNEWS.org

plateletnews.org — “plateletNEWS.orgView full resource at plateletnews.org

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Most Recently Shared on March 13, 2009 at 6:48 pm By:

plateletNEWS plateletNEWS.org Cardiology and Health Site

Poll: Do you prescribe dual antiplatelet therapy to patients presenting with ACS on admission? Respond here: http://bit.ly/15oJt

3 years ago...

Clopidogrel gene and stent thrombosis

theheart.org — “A polymorphism in one of the genes responsible for metabolizing clopidogrel to its active form has been shown to be associated with an increased risk of stent thrombosis in patients undergoing PCI. (Sibbing D et al. Eur Heart J; published online before print February 4, 2009.)View full resource at theheart.org

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Most Recently Shared on February 12, 2009 at 11:36 pm By:

theheartorg Shelley Wood Cardiology

Clopidogrel gene mutation linked to higher rate of stent thrombosis http://tinyurl.com/cxm6jp

3 years ago...

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