New Tool For RNA Silencing

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New Tool For RNA Silencing

medicalnewstoday.com

Anti-sense reagents have been developed for C. elegans micro RNA. Researchers writing in BioMed Central's open access journal Silence have created the first class of reagents to pote

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Tags: Genetic

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Most Recently Shared on April 4, 2010 at 2:04 pm By:

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Alnylam

alnylam.com — “Alnylam PharmceuticalsView full resource at alnylam.com

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Our scientists discovered new method 4 monitoring RNAi activity in blood samples; poster @Keystone: Silencing smallRNA: http://t.co/P11jLTsw

2 months ago...

Understanding interference | Harvard Gazette

news.harvard.edu — “In a discovery that might eventually lead to new biomedical treatments for disease, researchers from Harvard’s Department of Molecular and Cellular Biology have identified two types of RNA that are able to move between cells as part of a process called RNA-interference (RNAi).View full resource at news.harvard.edu

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Most Recently Shared on October 31, 2011 at 5:49 pm By:

JeffreyBlandPhD Jeffrey Bland, PhD Health Professional and Health Executive

Researchers @Harvard report step fwd in research on RNA-intrfrnce &gene silencing,could lead 2treatmnt 4genetic disease http://t.co/11THMKCo

6 months ago...

Understanding interference | Harvard Gazette

news.harvard.edu — “In a discovery that might eventually lead to new biomedical treatments for disease, researchers from Harvard’s Department of Molecular and Cellular Biology have identified two types of RNA that are able to move between cells as part of a process called RNA-interference (RNAi).View full resource at news.harvard.edu

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Most Recently Shared on October 30, 2011 at 5:17 am By:

Marina Biotech pins new hopes on patents for RNAi revival - FierceDrugDelivery

fiercedrugdelivery.com — “If not for a delivery problem, gene-silencing siRNA therapy would be much closer to reality inside the clinic today. Marina Biotech ($MRNA) of Bothell, WA, which develops RNAi-based compounds and Read more >>View full resource at fiercedrugdelivery.com

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Most Recently Shared on September 14, 2011 at 12:48 pm By:

JohnCFierce John Carroll Health Communicator

The big RNAi focus now is on delivery RT @FierceBiotech: Marina Biotech pins new hopes on patents for RNAi revival. http://t.co/gnMBRAr

7 months ago...

Potential New Gene Therapy Takes Out "Toxic" Genes to Treat Muscular Dystrophy

newswise.com — “Investigators at The Research Institute at Nationwide Children’s Hospital are studying a potential new treatment strategy for dominant forms of muscular dystrophy, using RNA interference to silence genes connected with the disease.View full resource at newswise.com

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Most Recently Shared on September 9, 2011 at 6:04 pm By:

mednewswise Thom Canalichio Health News

#health news: Potential New Gene Therapy Takes Out "Toxic" Genes to Treat Muscular Dystrophy: Investigators at T... http://t.co/P1DhaTK

7 months ago...

New resource to unlock the role of microRNAs

sciencedaily.com — “The first mammalian microRNA knockout resource -- mirKO -- will soon be released. This research toolbox of mutant mouse ES cells, in which individual or clustered groups of microRNA genes have been deleted, will help researchers define the role of microRNAs in health and disease. Using these tools researchers can create cells or mice lacking specific microRNAs, study expression using fluorescent markers, or inactivate the gene in specific tissues or at specific times in development.View full resource at sciencedaily.com

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Most Recently Shared on August 7, 2011 at 7:23 pm By:

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New resource to unlock the role of microRNAs: The first mammalian microRNA knockout resource -- mirKO -- w... http://tinyurl.com/3eyewqr

8 months ago...

New resource to unlock the role of microRNAs

medicalxpress.com — “A new resource to define the roles of microRNAs is announced today in Nature Biotechnology. The resource, called mirKO, gives researchers access to tools to investigate the biological role and significance for human health of these enigmatic genes.View full resource at medicalxpress.com

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Most Recently Shared on August 7, 2011 at 5:38 pm By:

Researchers Develop Powerful Fluorescence Tool, Light The Way To New Insights Into RNA Of Living Cells

medicalnewstoday.com — “The ability to tag proteins with a green fluorescent light to watch how they behave inside cells so revolutionized the understanding of protein biology that it earned the scientific teams who deveView full resource at medicalnewstoday.com

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Most Recently Shared on July 30, 2011 at 9:05 am By:

mnt_biology MNT Biology News Health News

Researchers Develop Powerful Fluorescence Tool, Light The Way To New Insights Into RNA Of Living Cells http://mnt.to/3YDN #biology

9 months ago...

New genetic technique probes the cause of skin cell differentiation in mammals

sciencedaily.com — “A tremendous amount of genetics research has been done in flies and tiny worms, in part because scientists have good tools for tweaking these creatures' DNA. Now, by adapting a powerful method of RNA interference for use in mice, researchers have identified key pathways that cause skin cells to differentiate, eventually forming the flexible but protective outer casing of the body. The work illustrates the potential for performing relatively fast and complex genetic studies in a fellow mammal, anView full resource at sciencedaily.com

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Most Recently Shared on April 8, 2011 at 1:31 am By:

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New genetic technique probes the cause of skin cell differentiation in mammals: A tremendous amount of genetics ... http://bit.ly/emNI55

1 year ago...

New gene therapy product reduces plasma cholesterol levels

news-medical.net — “Amsterdam Molecular Therapeutics (AMT) Holding N.V. a leader in the development of gene based therapies, today announced that its gene therapy product incorporating siRNA sequences into microRNA scaffolds to silence Apolipoprotein B100 (AAV-miApoB) was able to significantly lower plasma cholesterol levels in vivo over a period of 18 weeks. These preliminary results suggest that this approach could lead to a treatment for high cholesterol in humansView full resource at news-medical.net

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Most Recently Shared on October 25, 2010 at 10:20 am By:

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Parkinson's Disease: New gene therapy product reduces plasma cholesterol levels: Amsterdam Molecular Therapeutics ... http://bit.ly/cyd3Dz

1 year ago...

Screening tool can detect colorectal cancer from a small blood sample

sciencedaily.com — “A new microRNA screening assay detected the majority of early stage colorectal cancers with good specificity and sensitivity.View full resource at sciencedaily.com

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Most Recently Shared on September 30, 2010 at 3:14 pm By:

hopkinscrc Hopkins Colon Cancer Hospital

New Screening test detects colorectal cancer from a tiny blood sample, check it out!! http://bit.ly/cjyZt8

2 years ago...

Screening tool can detect colorectal cancer from a small blood sample

physorg.com — “A new microRNA (miRNA) screening assay detected the majority of early-stage colorectal cancers with good specificity and sensitivity.View full resource at physorg.com

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Most Recently Shared on September 29, 2010 at 11:00 pm By:

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Screening tool can detect colorectal cancer from a small blood sample http://tw.physorg.com/204998148

2 years ago...

Screening Tool Can Detect Colorectal Cancer from a Small Blood Sample

newswise.com — “1) Robust profiling of miRNAs from plasma is feasible using LNA"-enhanced technology; 2) miRNA profiles in plasma can detect early-stage colorectal cancer; 3) Plasma miRNA is a promising new biomarker for diseases, including cancer.View full resource at newswise.com

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Most Recently Shared on September 29, 2010 at 8:30 pm By:

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Screening Tool Can Detect Colorectal Cancer from a Small Blood Sample: 1) Robust profiling of miRNAs from plasma i... http://bit.ly/8ZmzIj

2 years ago...

First Theoretical Description Of Bacterial System To Silence Viral Genes

medicalnewstoday.com — “In a new study this week, Rice University scientists bring the latest tools of computational biology to bear in examining how the processes of natural selection and evolution influence the way bacView full resource at medicalnewstoday.com

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Most Recently Shared on September 20, 2010 at 12:05 pm By:

mnt_genetics MNT Genetics News Health News

First Theoretical Description Of Bacterial System To Silence Viral Genes http://mnt.to/3JWr #genetics

2 years ago...

MicroRNA linked to shut-down of DNA-repair genes

sciencedaily.com — “New research shows that microRNA can silence genes that protect against cancer-causing mutations. The study found that microRNA-155 can inhibit the activity of mismatch repair genes, which normally correct damage that occurs when the wrong bases are paired in DNA. Loss of these genes causes cancer-susceptibility syndromes and can contribute to colorectal, uterine, ovarian, and other cancers. It is the first evidence that deregulation of microRNAs can cause genomic instability, a characteristic oView full resource at sciencedaily.com

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Most Recently Shared on April 30, 2010 at 6:10 pm By:

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MicroRNA linked to shut-down of DNA-repair genes: New research shows that microRNA can silence genes that protect ... http://bit.ly/ckYCIY

2 years ago...

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