New Breast Cancer Tumor Suppressor Identified
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New Breast Cancer Tumor Suppressor Identified
View full resource at medicalnewstoday.com
Tags: Cancer, Breast Cancer, Protein, Genes, Women's Health
Most Recently Shared on June 28, 2011 at 11:05 am By:
New Breast Cancer Tumor Suppressor Identified http://mnt.to/3XJh #breastcancer
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Stronger intestinal barrier may prevent cancer in the rest of the body, new study suggests
sciencedaily.com — “A leaky gut may be the root of some cancers forming in the rest of the body, a new study suggests. It appears that the hormone receptor guanylyl cyclase C (GC-C) -- a previously identified tumor suppressor that exists in the intestinal tract -- plays a key role in strengthening the body's intestinal barrier, which helps separate the gut world from the rest of the body, and possibly keeps cancer at bay. Without the receptor, that barrier weakens.” View full resource at sciencedaily.com
Most Recently Shared on February 23, 2012 at 9:05 pm By:
Reducing intestinal permeability may reduce cancer risk: http://t.co/kTJu8n3M
SABCS: Loss of RB in Triple Negative Breast Cancer Associated with Favorable Clinical Outcome
newswise.com — “Researchers at the Thomas Jefferson University Hospital and Kimmel Cancer Center at Jefferson have shown that loss of the retinoblastoma tumor suppressor gene (RB) in triple negative breast cancer patients is associated with better clinical outcomes. This is a new marker to identify the subset of these patients who may respond positively to chemotherapy.” View full resource at newswise.com
Most Recently Shared on December 12, 2011 at 8:41 pm By:
New biomarker identified to help #breast #cancer patients decide if chemotherapy is right for them. http://t.co/P8VboP8Q #womenshealth
New potential target to slow breast cancer tumor progression and metastasis
news-medical.net — “A new potential target to slow breast cancer tumor progression and metastasis has been identified by a team of researchers led by Dr. Richard Kremer from the Research Institute of the McGill University Health Centre.” View full resource at news-medical.net
Most Recently Shared on November 11, 2011 at 10:12 am By:
Breast Cancer News: New potential target to slow breast cancer tumor progression and metastasis: A new potential... http://t.co/tRpfRpdB
Study identifies SIRT2 tumor suppressor protein linked to cancer
news-medical.net — “The list of aging-associated proteins known to be involved in cancer is growing longer, according to research by investigators at Vanderbilt-Ingram Cancer Center and the National Institutes of Health.” View full resource at news-medical.net
Most Recently Shared on October 18, 2011 at 10:19 am By:
Cancer News Study identifies SIRT2 tumor suppressor protein linked to cancer: The list of aging-associated prote... http://t.co/g6a9UKxg
Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155 : Nature Medicine : Nature Publishing Group
nature.com — “BRCA1 loss of function is considered to promote tumorigenesis through impairment of the protein's role in DNA damage repair. By studying BRCA1 mutations that do not affect this function but still confer cancer predisposition, this report identifies a new function of BRCA1, the repression of miR-155 through modulation of HDAC activity. miR-155 increase correlates with BRCA1 loss or mutation in humans, and it likely to mediate some of the oncogenic effects of BRCA1 deficiency.” View full resource at nature.com
Most Recently Shared on September 26, 2011 at 5:23 pm By:
Study identifies a new function of BRCA1 http://j.mp/pUecHd (abstract) #breastcancer #microRNA
Study shows relationship between 2 mutated genes can dictate outcome of prostate cancer
eurekalert.org — “Being able to distinguish between the 1% of prostate cancer patients who will develop lethal disease and the majority of patients who will develop non-lethal cancer is a key goal in prostate cancer research. CSHL scientists have gotten closer to this goal by identifying a new prostate tumor suppressor gene called PHLPP1 and showing that it acts in concert with PTEN, a tumor suppressor that is mutated in roughly half of prostate cancer patients.” View full resource at eurekalert.org
Most Recently Shared on August 15, 2011 at 4:55 pm By:
Study shows relationship between 2 mutated genes can dictate outcome of prostate cancer: ( Cold Spring Harbor La... http://t.co/XRERY1L
Key metabolic pathway implicated in intractable form of breast cancer
sciencedaily.com — “Using a new in vivo screening system, researchers have identified a protein in a key metabolic pathway that is essential in estrogen receptor (ER)-negative breast cancer. When the expression of the gene that codes for this protein -- phosphoglycerate dehydrogenase or PHGDH -- is suppressed in tumors and cell lines with an overabundance of the protein, the rate of cellular growth declines markedly. PHGDH is overexpressed in approximately 70 percent of ER-negative breast cancer patients.” View full resource at sciencedaily.com
Most Recently Shared on July 19, 2011 at 11:33 pm By:
Key metabolic pathway implicated in intractable form of #breast #cancer: http://t.co/ByESZq6 via @AddThis #oncology
Key metabolic pathway implicated in intractable form of breast cancer
sciencedaily.com — “Using a new in vivo screening system, researchers have identified a protein in a key metabolic pathway that is essential in estrogen receptor (ER)-negative breast cancer. When the expression of the gene that codes for this protein -- phosphoglycerate dehydrogenase or PHGDH -- is suppressed in tumors and cell lines with an overabundance of the protein, the rate of cellular growth declines markedly. PHGDH is overexpressed in approximately 70 percent of ER-negative breast cancer patients.” View full resource at sciencedaily.com
Most Recently Shared on July 18, 2011 at 9:39 pm By:
Key metabolic pathway implicated in intractable form of breast cancer http://bit.ly/nM9FsB
Key metabolic pathway implicated in intractable form of breast cancer
sciencedaily.com — “Using a new in vivo screening system, researchers have identified a protein in a key metabolic pathway that is essential in estrogen receptor (ER)-negative breast cancer. When the expression of the gene that codes for this protein -- phosphoglycerate dehydrogenase or PHGDH -- is suppressed in tumors and cell lines with an overabundance of the protein, the rate of cellular growth declines markedly. PHGDH is overexpressed in approximately 70 percent of ER-negative breast cancer patients.” View full resource at sciencedaily.com
Most Recently Shared on July 18, 2011 at 9:21 pm By:
Key metabolic pathway implicated in intractable form of breast cancer: Using a new in vivo screening syste... http://tinyurl.com/3wu28th
Potent Breast Cancer Tumor Suppressor Identified
medicalnewstoday.com — “Researchers have identified the gene-regulating protein Runx3 as a potent suppressor of tumor growth in breast cancer and found that it most likely does this by regulating cellular response to c” View full resource at medicalnewstoday.com
Most Recently Shared on June 28, 2011 at 9:05 am By:
Potent Breast Cancer Tumor Suppressor Identified http://mnt.to/3XJD #healthnews
Team identifies new breast cancer tumor suppressor and how it works
eurekalert.org — “Researchers have identified a protein long known to regulate gene expression as a potent suppressor of breast cancer growth. Their study, in the journal Oncogene, is the first to demonstrate how this protein, known as Runx3, accomplishes this feat.” View full resource at eurekalert.org
Most Recently Shared on June 27, 2011 at 9:58 pm By:
Team identifies new #breastcancer tumor suppressor and how it works http://ping.fm/Ql5fP
Signaling Pathways Point to Vulnerability in Breast Cancer Stem Cells - ScienceNewsline
sciencenewsline.com — “CAMBRIDGE, Mass. (June 9, 2011) – Whitehead Institute researchers have identified signals from breast epithelial cells that can induce those cells to transition to and maintain a mesenchymal and stem cell-like cell state that imbues both normal and cancer cells with a greater ability to migrate and self-renew. Interrupting these signals strips the cells of the migratory, invasive and self-renewal abilities used by cancer stem cells to seed new tumors.” View full resource at sciencenewsline.com
Most Recently Shared on June 15, 2011 at 2:15 pm By:
ScienceNewsOnline: "Signaling Pathways Point to Vulnerability in #BreastCancer Stem Cells " http://ow.ly/5idHl
Medical News: FDA Clears Improved HER2 Test in Breast Cancer - in Oncology/Hematology, Breast Cancer from MedPage Today
medpagetoday.com — “The FDA has approved a new quantitative test for HER2 genes in breast tumor samples that can be performed under a standard microscope, potentially making it easier to identify patients who would benef” View full resource at medpagetoday.com
Most Recently Shared on June 15, 2011 at 1:25 pm By:
FDA Clears Improved HER2 Test in Breast Cancer http://bit.ly/loaX1B
Signaling Pathways Point to Vulnerability in Breast Cancer Stem Cells
newswise.com — “Whitehead Institute researchers have identified signals impinging on breast epithelial cells that can induce those cells to acquire and stably display migratory and self-renewing characteristics. Interrupting these and other extracellular signals strips the various types of stem cells of the migratory and self-renewal abilities used by cancer stem cells to seed new tumors.” View full resource at newswise.com
Most Recently Shared on June 9, 2011 at 5:02 pm By:
#health news: Signaling Pathways Point to Vulnerability in Breast Cancer Stem Cells: Whitehead Institute researc... http://bit.ly/jSVPC9
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Potent Breast Cancer Tumor Suppressor Identified http://mnt.to/3XJD #genetics
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