Neural Degeneration in the Retina of the Streptozotocin-Induced Type 1 Diabetes Model

Links shared publicly online about this topic.

0
total visits

Neural Degeneration in the Retina of the Streptozotocin-Induced Type 1 Diabetes Model

Diabetic retinopathy, a vision-threatening disease, has been regarded as a vascular disorder. However, impaired oscillatory potentials (OPs) in the electroretinogram (ERG) and visual dysfunction are recorded before severe vascular lesions appear. Here, we review the molecular mechanisms underlying the retinal neural degeneration observed in the streptozotocin-(STZ-) induced type 1 diabetes model. The renin-angiotensin system (RAS) and reactive oxygen species (ROS) both cause OP impairment and re

View full resource at hindawi.com

Tags: Diabetes, Type 1 Diabetes, Eye, Disease and Condition, disease, Diabetic Retinopathy, Retina