Move over Prozac: New drug offers hope for depression

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Move over Prozac: New drug offers hope for depression

The brain chemistry that underlies depression is incompletely understood, but research suggests that aberrant signaling by a chemical called brain-derived neurotrophic factor through its receptor TrkB, may contribute to anxiety and depression. Here, researchers describe a screen for stable small molecules that could specifically inhibit TrkB action. They identified one they dubbed ANA-12, which had potent behavioral effects when administered to mice that suggest it will have antidepressant and a

View full resource at sciencedaily.com

Tags: Panic Disorder Medication, Obsessive-Compulsive Disorder Medication, PTSD Medication, Depression, Antidepressant, Drug, Prozac

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Move over Prozac: New drug offers hope for depression

sciencedaily.com — “The brain chemistry that underlies depression is incompletely understood, but research suggests that aberrant signaling by a chemical called brain-derived neurotrophic factor through its receptor TrkB, may contribute to anxiety and depression. Here, researchers describe a screen for stable small molecules that could specifically inhibit TrkB action. They identified one they dubbed ANA-12, which had potent behavioral effects when administered to mice that suggest it will have antidepressant and a” View full resource at sciencedaily.com