Molecular and Therapeutic Potential and Toxicity of Valproic Acid
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Molecular and Therapeutic Potential and Toxicity of Valproic Acid
Valproic acid (VPA), a branched short-chain fatty acid, is widely used as an antiepileptic drug and a mood stabilizer. Antiepileptic properties have been attributed to inhibition of Gamma Amino Butyrate (GABA) transaminobutyrate and of ion channels. VPA was recently classified among the Histone Deacetylase Inhibitors, acting directly at the level of gene transcription by inhibiting histone deacetylation and making transcription sites more accessible. VPA is a widely used drug, particularly for c
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Molecular and Therapeutic Potential and Toxicity of Valproic Acid: Valproic acid (VPA), a branched short-chain fat... http://bit.ly/bZXuRe
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