Mgat5 Deficiency in T Cells and Experimental Autoimmune Encephalomyelitis
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Mgat5 Deficiency in T Cells and Experimental Autoimmune Encephalomyelitis
Multiple sclerosis (MS) is an inflammatory demyelinating and neurodegenerative disease initiated by autoreactive T cells. , a gene in the Asn (N-) linked protein glycosylation pathway, associates with MS severity and negatively regulates experimental autoimmune encephalomyelitis (EAE) and spontaneous inflammatory demyelination in mice. N-glycan branching by regulates interaction of surface glycoproteins with galectins, forming a molecular lattice that differentially controls the concentration of
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Tags: Multiple Sclerosis, Disease and Condition, Protein, Genes, disease
Most Recently Shared on August 19, 2011 at 6:43 am By:
Mgat5 Deficiency in T Cells and Experimental Autoimmune Encephalomyelitis: Multiple sclerosis (MS) is an inflamm... http://t.co/DUNBeDF
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