Low-dose diazepam with NS-398 combination has twice the neuroprotective effect of NS-398 alone

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Low-dose diazepam with NS-398 combination has twice the neuroprotective effect of NS-398 alone

news-medical.net

Status epilepticus, prolonged seizures, can lead to significant neurological deficits and, rarely, even death. The anticonvulsant diazepam, a first line therapy for the condition, is neuroprotective when administered in high doses within two hours from seizure onset. Researchers at the 64th AES Annual Meeting now report that the combination of low-dose diazepam and NS-398, a COX-2 inhibitor, has twice the neuroprotective effect of NS-398 alone.

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Tags: Neurology, Seizure, Epilepsy, Anxiety Medication, Valium, News, Mortality

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