JNI | Full text | Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice
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JNI | Full text | Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice
Chronic neuroinflammation is implicated in Parkinson's disease (PD). Inflammation involves the activation of microglia and astrocytes that release high levels of prostaglandins. There is a profound gap in our understanding of how cyclooxygenases and their prostaglandin products redirect cellular events to promote PD neurodegeneration. The major prostaglandin in the mammalian brain is prostaglandin D2, which readily undergoes spontaneous dehydration to generate the bioactive cyclopentenone prosta
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Tags: Brain, Parkinson's Disease, Disease and Condition, disease, Event
Most Recently Shared on July 26, 2009 at 2:30 pm By:
New pub on Parkinson's and inflammation: http://www.jneuroinflammation.com/content/6/1/18
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