International team identifies 21 new genetic risk factors for Crohn's disease

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International team identifies 21 new genetic risk factors for Crohn's disease

An international consortium of Crohn's disease researchers has combined data from three independent studies to identify 21 new genetic variants associated with the inflammatory bowel disorder, bringing the total number of risk factors to 32. Several of these are involved with the immune system's inital response to pathogens, supporting earlier evidence that disruptions in a process called autophagy may lead to the disorder's characteristic immune system overactivity.

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Tags: Immune, IBD, Crohn's Disease, Genetic, Disease and Condition