Hypersensitivity Reactions Associated with Platinum Antineoplastic Agents: A Systematic Review

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Hypersensitivity Reactions Associated with Platinum Antineoplastic Agents: A Systematic Review

Platinum-containing chemotherapy agents (cisplatin, carboplatin, oxaliplatin) have been approved in the first-line setting of numerous malignancies, such as ovarian, bladder, head and neck, colorectal, and lung cancer. Their extensive use over the last decade has led to a significant increase in the incidence of hypersensitivity reactions, which are defined as unforeseen reactions whose signs and symptoms cannot be explained by the known toxicity of these drugs. Skin rash, flushing, abdominal cr

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Tags: Chemotherapy, Malignancy, Colorectal Cancer Medication, Lung, Urinary System, Women's Health, Eloxatin, Eloxatine