Gene Variations Associated With Risk Of Type 2 Diabetes

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Gene Variations Associated With Risk Of Type 2 Diabetes

medicalnewstoday.com

For individuals of white European descent, certain variations of the gene HMGA1 are associated with type 2 diabetes mellitus, according to a study in the March 2 issue of JAMA. Type 2 diabetes mel

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Tags: Diabetes, Type 2 Diabetes, Genes

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Gene Variations Associated With Risk Of Type 2 Diabetes - For individuals of white European descent, certain variati... http://ow.ly/1bznkj

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Largest-ever gene study of Type 2 diabetes finds variants across many ethnic groups

eurekalert.org — “The largest genetics study to date of Type 2 diabetes has identified new gene variants associated with risk for the common metabolic disease. An international scientific consortium, studying multi-ethnic populations, uncovered genes that may point to biological targets for developing more effective drugs for T2D.View full resource at eurekalert.org

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eurekalert.org — “A combination of genetic and environmental factors causes an individual to develop Type 2 diabetes. Among the most reproducible genetic variations associated with the disease are those in the CDKAL1 gene. However, the mechanisms underlying these associations have not yet been determined. But now, researchers have generated evidence in mice that could potentially explain why individuals carrying certain variants of the CDKAL1 gene are at increased risk of developing Type 2 diabetes.View full resource at eurekalert.org

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Researchers discover how a gene linked to Type 2 diabetes causes decreased insulin production. http://t.co/iw7LVA4

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Study finds possible reason behind high diabetes rates in blacks - Related Stories - DiabetesPro SmartBrief

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polygenicpathways.blogspot.com — “Concerning the relationships between genes, risk factors and immunity in Alzheimer's disease, Autism, Bipolar disorder , multiple sclerosis, Parkinson's disease, schizophrenia and chronic fatigueView full resource at polygenicpathways.blogspot.com

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Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in… http://goo.gl/fb/YxaQ8

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PolygenicBlog: LDL-associated apolipoprotein J (clusterin) and lysozyme are associated with atherogenic properties of LDL found in type 2 diabetes and the metabolic syndrome.

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The rs1014290 Polymorphism of the SLC2A9 Gene Is Associated with Type 2 Diabetes Mellitus in Han Chinese

hindawi.com — “Aims. The SLC2A9 gene encodes the glucose transporter 9, with the abilities of transporting both glucose and uric acid and is involved in the pancreatic glucose-stimulated insulin secretion. The single nucleotide polymorphisms (SNPs) of SLC2A9 accounted for 5% variance of serum uric acid (UA). UA was identified as a risk factor for type 2 diabetes mellitus (DM). We investigated whether the SLC2A9 gene variations are associated with type 2 DM in Han Chinese. Methods. Three common SNPs of the SLC2View full resource at hindawi.com

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Silencing a gene may benefit cardiovascular health of diabetics

endocrineweb.com — “Silencing a particular gene may eliminate much of the cardiovascular risk associated with type 1 and type 2 diabetes, according to a new study from Canadian researchers.By using genetically programmed mice for the study, scientists from the University of Western Ontario were able to analyze the effects of eliminating certain genes from their DNA.View full resource at endocrineweb.com

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UNC team discovers mechanistic link between genetic variation and risk of atherosclerotic disease —

news.unchealthcare.org — “Previous genome-wide association studies (GWAS) have shown that common genetic variants located near these genes are associated with diseases of aging such as cancer, heart attack, stroke, type 2 diabetes and frailty. Yet how these variants contribute to the risk of these ailments was not known.View full resource at news.unchealthcare.org

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#UNC team discovers mechanistic link between genetic variation and risk of atherosclerotic disease. http://uncmedne.ws/rna #SITT

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MedWire News - Diabetes - NFATC2 variation linked to rosiglitazone-induced edema

medwire-news.md — “MedWire News Variation in the NFATC2 gene is associated with increased risk for rosiglitazone-associated edema, show results from a subanalysis of the DREAM trial. MedWire NewsView full resource at medwire-news.md

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polygenicpathways.blogspot.com — “Concerning the relationships between genes, risk factors and immunity in Alzheimer's disease, Autism, Bipolar disorder , multiple sclerosis, Parkinson's disease, schizophrenia and chronic fatigueView full resource at polygenicpathways.blogspot.com

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medicalnewstoday.com — “Examination of a gene involved in cell signaling finds that four common variants of this gene are associated with the development of end-stage renal disease in Chinese patients with type 2 diabeteView full resource at medicalnewstoday.com

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