Fluorouracil Toxicity and DPYD: eMedicine Genomic Medicine
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Fluorouracil Toxicity and DPYD: eMedicine Genomic Medicine
Overview: 5-Fluorouracil (5FU) is a fluorinated pyrimidine analogue commonly used in combination chemotherapy regimens for patients with breast, colorectal, lung, and other malignancies. Dihydropyrimidine dehydrogenase (DPD), an enzyme encoded by the DPYD gene, is the rate-limiting ...
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Tags: Poison, Chemotherapy, Colorectal Cancer Medication, Women's Health, 5-FU, Adrucil, Efudex, Genomic Medicine
Most Recently Shared on June 2, 2010 at 7:58 pm By:
Patients with known or suspected DPD deficiency are generally advised to avoid therapy with 5FU/capecitabine. Learn why.http://bit.ly/bclkvC
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