Engineered, drug-secreting blood vessels reverse anemia in mice

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Engineered, drug-secreting blood vessels reverse anemia in mice

Patients who rely on recombinant, protein-based drugs must often endure frequent injections, often several times a week, or intravenous therapy. Researchers have demonstrated the possibility that blood vessels, made from genetically engineered cells, could secrete the drug on demand directly into the bloodstream. In a new study, they provide proof-of-concept, reversing anemia in mice with engineered vessels secreting erythropoietin (EPO).

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Tags: Circulation, Anemia, Anemia Medication, Kidney Health, Urinary System, Drug