Doubling clopidogrel dose in ACS

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Doubling clopidogrel dose in ACS

theheart.org

UPDATED WITH COMMENTARY // Doubling the loading and maintenance doses of clopidogrel in acute coronary syndrome patients who underwent planned PCI significantly reduces stent thrombosis and cardiovascular events, largely driven by reductions in MI, without a significant increase in major bleeding, report researchers.

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Tags: Bleeding, Disease and Condition, Anti-Clotting Medication, Plavix, Iscover

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Most Recently Shared on August 30, 2009 at 3:55 pm By:

theheartorg Shelley Wood

heartwire: CURRENT OASIS-7: Benefit to doubling clopidogrel dose in ACS patients undergoing PCI http://bit.ly/12xYSx

3 years ago...

Cilostazol Matches Double-Dose Clopidogrel Following PCI : Cardiology News

ecardiologynews.com — “Cardiology News is an independent news source that provides cardiologists with timely and relevant news and commentary about clinical developments and the impact of health care policy on cardiology and the cardiologist's practice. Cardiology News Digital Network is the online destination and multimedia properties of Cardiology News, the independent news publication for cardiologists. Cardiology news is the leading source of news and commentary about clinical developments in cardiology as well asView full resource at ecardiologynews.com

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Most Recently Shared on March 26, 2012 at 5:37 pm By:

CardioNews Cardiology News Cardiology and Health News

Cilostazol Matches Double-Dose Clopidogrel Following PCI http://t.co/ZqlJxFju

3 weeks ago...

Prasugrel Bests Double-Dose Clopidogrel in Clopidogrel Nonresponders : Cardiology News

ecardiologynews.com — “Cardiology News is an independent news source that provides cardiologists with timely and relevant news and commentary about clinical developments and the impact of health care policy on cardiology and the cardiologist's practice. Cardiology News Digital Network is the online destination and multimedia properties of Cardiology News, the independent news publication for cardiologists. Cardiology news is the leading source of news and commentary about clinical developments in cardiology as well asView full resource at ecardiologynews.com

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Most Recently Shared on March 25, 2012 at 4:34 pm By:

MedicalNewsNet Bob Finn - Medical News Net Health News

Patients on clopidogrel for stable coronary disease benefit more from switching to prasugrel than doubling the dose - http://t.co/96ca10hr

3 weeks ago...

Prasugrel Bests Double-Dose Clopidogrel in Clopidogrel Nonresponders : Cardiology News

ecardiologynews.com — “Cardiology News is an independent news source that provides cardiologists with timely and relevant news and commentary about clinical developments and the impact of health care policy on cardiology and the cardiologist's practice. Cardiology News Digital Network is the online destination and multimedia properties of Cardiology News, the independent news publication for cardiologists. Cardiology news is the leading source of news and commentary about clinical developments in cardiology as well asView full resource at ecardiologynews.com

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Most Recently Shared on March 25, 2012 at 3:47 pm By:

CardioNews Cardiology News Cardiology and Health News

Prasugrel Bests Double-Dose Clopidogrel in Clopidogrel Nonresponders http://t.co/h24S9qeO

3 weeks ago...

JAMA: Platelet testing shows promise, but still no reason for widespread adoption

cardiovascularbusiness.com — “Among patients with acute coronary syndromes (ACS) undergoing a procedure such as angioplasty, those who received platelet function tests before receiving anti-thrombotic therapy to determine appropriate clopidogrel dosing and who had high residual platelet reactivity were at an increased risk of an ischemic event at short- and long-term follow-up of up to two years, according to the results of the RECLOSE 2-ACS study in the Sept. 21 issue of the Journal of the American Medical Association. HoweView full resource at cardiovascularbusiness.com

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Most Recently Shared on September 21, 2011 at 4:29 pm By:

CardioBusiness CardioBusiness Health Magazine

JAMA: Platelet testing shows promise, but still no reason for widespread adoption http://t.co/b1QxyRLi

7 months ago...

HRPR before PCI procedures linked to increased risk of ischemic event in ACS patients

news-medical.net — “Among patients with acute coronary syndromes undergoing a procedure such as angioplasty, those who received platelet function tests before receiving antithrombotic therapy to determine appropriate clopidogrel dosing and who had high residual platelet reactivity were at an increased risk of an ischemic event at short- and long-term follow-up of up to 2 years, according to a study in the September 21 issue of JAMA.View full resource at news-medical.net

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Most Recently Shared on September 21, 2011 at 12:09 pm By:

Stroke_News News-Medical.Net Health News

Stroke News: HRPR before PCI procedures linked to increased risk of ischemic event in ACS patients: Among pati... http://t.co/nmPz3eUp

7 months ago...

ScienceDirect - Thrombosis Research : Doubling the dose of Clopidogrel restores the loss of antiplatelet effect induced by esomeprazole

sciencedirect.com — “ScienceDirect - Thrombosis Research : Doubling the dose of Clopidogrel restores the loss of antiplatelet effect induced by esomeprazoleView full resource at sciencedirect.com

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Most Recently Shared on July 27, 2011 at 10:37 pm By:

virtualneuronet Edgar Avalos, MD Neurology and Health Group

Doubling the dose of Clopidogrel restores the loss of antiplatelet effect induced by esomeprazole http://t.co/nOuxLmH

9 months ago...

Poor Clopidogrel Responders With ACS Face High Risk of Death - QualityPoint Technologies

qualitypointtech.net — “After a number of negative trials in stable coronary disease, the RECLOSE 2 ACS study, using light-transmittance aggregometry to assess platelet reactivity, shows that ACS nonresponders to clopidogrel face much higher rates of adverse ischemic events and cardiac death after PCI than responders and that doubling the clopidogrel dose doesn't improve their odds. HeartwireView full resource at qualitypointtech.net

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Most Recently Shared on May 19, 2011 at 11:00 pm By:

MedicalFeed MedicalFeed Health News Feed

Poor Clopidogrel Responders With ACS Face High Risk of Death: After a number of negative trials in stable coronary... http://bit.ly/lJHUkG

11 months ago...

Medical News: Double Dose Plavix No Benefit After Stenting - in Cardiovascular, PCI from MedPage Today

medpagetoday.com — “A double dose of clopidogrel (Plavix) following percutaneous coronary intervention does not appear to reduce cardiovascular events among stent patients with high platelet reactivity on a standard doseView full resource at medpagetoday.com

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Most Recently Shared on March 16, 2011 at 9:36 pm By:

Medical News: Double Dose Plavix No Benefit After Stenting - in Cardiovascular, PCI from MedPage Today

medpagetoday.com — “A double dose of clopidogrel (Plavix) following percutaneous coronary intervention does not appear to reduce cardiovascular events among stent patients with high platelet reactivity on a standard doseView full resource at medpagetoday.com

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Most Recently Shared on March 16, 2011 at 2:37 pm By:

MedicalNews Medical News Health News

Double Dose Plavix No Benefit After Stenting (CME/CE) http://bit.ly/eJjTxL

1 year ago...

GRAVITAS Trial finds high dose of clopidogrel does not reduce risk of ischemic events

news-medical.net — “Accumetrics, Inc., developer and marketer of the VerifyNow System, today announced that the GRAVITAS (Gauging Responsiveness With A VerifyNow Assay-Impact On Thrombosis And Safety) Trial found that in patients with high residual platelet reactivity, doubling the maintenance dose of clopidogrel did not reduce the risk of further ischemic events after percutaneous coronary intervention (PCI).View full resource at news-medical.net

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Most Recently Shared on November 19, 2010 at 8:26 pm By:

Stroke_News News-Medical.Net Health News

Stroke News: GRAVITAS Trial finds high dose of clopidogrel does not reduce risk of ischemic events: Accumetric... http://twurl.nl/hydpwz

1 year ago...

Internal Medicine Article -

mdlinx.com — “Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): A randomised factorial trialView full resource at mdlinx.com

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Most Recently Shared on November 1, 2010 at 11:50 am By:

MDLinx Sandeep Pulim MD Physician, Doctor, and Health Communicator

Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergo... http://bit.ly/9SEOv2 #medicine

1 year ago...

Phase II Study Showed Switching ACS-PCI Patients To Effient®/aspirin From Plavix®/aspirin Regimen Reduced Maximum Platelet Aggregation

medicalnewstoday.com — “A study evaluating the level of platelet aggregation achieved after switching from Plavix® (clopidogrel) 75 mg once-daily maintenance dosing plus aspirin to Effient® (prasugrel) 10 mg oncView full resource at medicalnewstoday.com

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Most Recently Shared on September 14, 2010 at 1:38 pm By:

mnt_clinical MNT Clinical Trials Health News

Phase II Study Showed Switching ACS-PCI Patients To Effient®/aspirin From Plavix®/aspirin Regimen Reduced Maxi... http://mnt.to/3JHJ

2 years ago...

Switching ACS patients to Effient therapy reduces Maximum Platelet Aggregation

news-medical.net — “A study evaluating the level of platelet aggregation achieved after switching from Plavix (clopidogrel) 75 mg once-daily maintenance dosing plus aspirin to Effient(prasugrel) 10 mg once-daily maintenance dosing (MD) in patients with acute coronary syndrome (ACS) was published today in the Journal of the American College of Cardiology.View full resource at news-medical.net

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Most Recently Shared on September 14, 2010 at 7:28 am By:

Stroke_News News-Medical.Net Health News

Stroke News: Switching ACS patients to Effient therapy reduces Maximum Platelet Aggregation: A study evaluating ... http://twurl.nl/jqo0zn

2 years ago...

Double-Dose Clopidogrel Reduces Risk Of Death, Heart Attack Or Stroke In Patients Undergoing Angioplasty

medicalnewstoday.com — “A double-dose of the anti-clotting treatment clopidogrel, also known as Plavix, significantly reduces complications in heart patients undergoing angioplasty to clear blocked arteries.ShamView full resource at medicalnewstoday.com

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Most Recently Shared on September 3, 2010 at 3:00 pm By:

mnt_stroke MNT Stroke News Health News

Double-Dose Clopidogrel Reduces Risk Of Death, Heart Attack Or Stroke In Patients Undergoing Angioplasty http://mnt.to/3JfD #stroke

2 years ago...

Clopidogrel Dosing and CYP2C19: eMedicine Genomic Medicine

emedicine.medscape.com — “Overview: Clopidogrel (Plavix), a second-generation thienopyridine that inhibits platelet aggregation, is a mainstay, along with aspirin, in the management of patients with coronary artery disease, with acute coronary syndromes (ACS), and/or after percutaneous coronary interventions (PCI). Yet, a ...View full resource at emedicine.medscape.com

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Most Recently Shared on June 2, 2010 at 7:44 pm By:

Health_SS Susan S Health Advocate

Clopidogrel carries an increased risk of cardiovascular death in those with a certain chromosomal abnormalities. http://bit.ly/av2Ace

2 years ago...

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