CYP450 Metabolite Significantly Increased in Rofecoxib-Treated Mice - QualityPoint Technologies
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CYP450 Metabolite Significantly Increased in Rofecoxib-Treated Mice - QualityPoint Technologies
The oral administration of rofecoxib resulted in a significant increase in blood levels of 20-hydroxyeicosatetraenoic acid, a potent vasoconstrictor, and this metabolite was also shown to significantly decrease tail bleeding times in a mouse model. Heartwire
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CYP450 Metabolite Significantly Increased in Rofecoxib-Treated Mice: The oral administration of rofecoxib resulted... http://bit.ly/c5wd4k
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