Clopidogrel genes and PPI

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Clopidogrel genes and PPI

theheart.org

The analysis also looked at the effect of PPIs and found that they were associated with an increased risk of events only in high-risk patients.

View full resource at theheart.org

Tags: Genes, Anti-Clotting Medication, Plavix, Iscover

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Most Recently Shared on July 5, 2010 at 9:45 pm By:

theheartorg Shelley Wood

New meta-analysis: CYP2C19*2 carriers at higher risks of events on clopidogrel: The analysis also looked at the ef... http://bit.ly/d1uIcH

2 years ago...

Clopidogrel and adverse cardiovascular events not linked - The Doctor's Channel

thedoctorschannel.com — “NEW YORK (Reuters Health) – There is no need to avoid proton pump inhibitors (PPIs) in patients on the platelet inhibitors clopidogrel or ticagrelor. The increased rates of adverse cardiovascular events in these patients are tied to baseline status rather than any drug...View full resource at thedoctorschannel.com

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Most Recently Shared on February 27, 2012 at 7:31 pm By:

doctorschannel Dr Michael Banks - The Doctor's Channel Health Site

Don't jump to conclusions ... especially in matters of the heart! - From Reuters Health/TDC http://t.co/cy2Q0cr0 #health #heart #PPI

2 months ago...

MedWire News - Thrombosis - Early stent thrombosis predictors identified

medwire-news.md — “MedWire News Variants in three genes associated with clopidogrel metabolism and platelet receptor function are independently associated with early stent thrombosis in patients undergoing percutaneous coronary intervention, study data show. MedWire NewsView full resource at medwire-news.md

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Most Recently Shared on October 27, 2011 at 9:25 am By:

MedWireNews MedWire News Health News

Early stent thrombosis predictors identified http://t.co/e1Dcb2dA

6 months ago...

Antiplatelet therapy: Clopidogrel-PPI interaction, an ongoing controversy : Article : Nature Reviews Cardiology

nature.com — “Antiplatelet therapy: Clopidogrel-PPI interaction, an ongoing controversy : Article : Nature Reviews CardiologyView full resource at nature.com

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Most Recently Shared on January 11, 2011 at 1:20 am By:

SympoCardiology Symposier Cardiology Cardiology and Health Business

Antiplatelet therapy: Clopidogrel–PPI interaction, an ongoing controversy. http://bit.ly/hJs1U7

1 year ago...

Next Steps in Pharmacogenomics: Topol on Genomics

boards.medscape.com — “A new, potentially quite important, variant of the gene PON1 influencing Plavix (clopidogrel) metabolism was just reported in Nature Medicine with an accompanying editorial that I prepared with my colleague Dr. Nicholas Schork. This discovery is instView full resource at boards.medscape.com

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Most Recently Shared on January 8, 2011 at 8:27 pm By:

westr westr Doctor, Health Social Media, and PhD

PON1-variant Reflections: "Some v-blog thoughts on progress in pharmacogenomics http://bit.ly/gysK4E" -via @EricTopol 4' vid #PM101

1 year ago...

Next Steps in Pharmacogenomics: Topol on Genomics

boards.medscape.com — “A new potentially quite important variant of the gene PON1 influencing Plavix (clopidogrel) metabolism was just reported in Nature Medicine with an accompanying editorial that I prepared with my colleague Dr. Nicholas Schork. This discovery is instruView full resource at boards.medscape.com

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Most Recently Shared on January 8, 2011 at 8:19 pm By:

Genetic variations linked with worse outcomes with use of antiplatelet drug for cardiac procedures

eurekalert.org — “An analysis of data from previously published studies indicates that use of the antiplatelet drug clopidogrel for patients who have common genetic variants of a certain gene and are undergoing a procedure such as coronary stent placement have an associated increased risk for major adverse cardiovascular events, particularly development of blood clots in stents, according to a study in the Oct. 27 issue of JAMA.View full resource at eurekalert.org

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Most Recently Shared on October 26, 2010 at 9:34 pm By:

Genetics_Wisdom Genetics OW OW Health

Genetic variations linked with worse outcomes with use of antiplatelet drug for cardiac procedures: ( JAMA and Arc... http://bit.ly/94oABn

1 year ago...

Gene Mutations May Blunt Plavix's Effectiveness, Study Finds - Drugs.com MedNews

drugs.com — “People with certain gene variants who take the blood-thinning drug Plavix (clopidogrel) may be at increased risk for serious complications after coronary stentView full resource at drugs.com

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Most Recently Shared on October 26, 2010 at 9:29 pm By:

drugscom Drugs.com Health Site

Gene Mutations May Blunt Plavix's Effectiveness, Study Finds - http://bit.ly/cTT53h

1 year ago...

Gene Mutations May Blunt Plavix's Effectiveness, Study Finds - Drugs.com MedNews

drugs.com — “People with certain gene variants who take the blood-thinning drug Plavix (clopidogrel) may be at increased risk for serious complications after coronary stentView full resource at drugs.com

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Most Recently Shared on October 26, 2010 at 9:13 pm By:

Drugs_Devices Drugs and Devices OW OW Health

Gene Mutations May Blunt Plavix's Effectiveness, Study Finds: TUESDAY, Oct. 26 -- People with certain gene va... http://bit.ly/bkpa2p #drug

1 year ago...

PolygenicBlog: Visceral Adiposity Index Directly Correlated To Viral Load In Genotype 1 Chronic Hepatitis C

polygenicpathways.blogspot.com — “Concerning the relationships between genes, risk factors and immunity in Alzheimer's disease, Autism, Bipolar disorder , multiple sclerosis, Parkinson's disease, schizophrenia and chronic fatigueView full resource at polygenicpathways.blogspot.com

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Most Recently Shared on October 23, 2010 at 11:37 pm By:

ChrisCarter http://www.linkedin.com/pub/chris-carter/22/560/76a" /> Dr Chris Carter Doctor, Medical Technology, Pharmacist, and PhD

Visceral Adiposity Index Directly Correlated To Viral Load In Genotype 1 Chronic Hepatitis C http://goo.gl/fb/PpyWK

2 years ago...

Vanderbilt clopidogrel gene testing | theheart.org

theheart.org — “Heartwire staff and renowned specialists in cardiology from Duke Clinical Research Institute and Mayo Clinic discuss latest developments in interventional surgery.View full resource at theheart.org

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Most Recently Shared on October 21, 2010 at 10:56 pm By:

EricTopol Eric Topol, MD Cardiologist, Physician, Doctor, and Internist

Another major center-Vanderbilt--now doing routine genotyping for Plavix loss of function variants http://bit.ly/9ZZ18k

2 years ago...

Vanderbilt clopidogrel gene testing | theheart.org

theheart.org — “Heartwire staff and renowned specialists in cardiology from Duke Clinical Research Institute and Mayo Clinic discuss latest developments in interventional surgery.View full resource at theheart.org

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Most Recently Shared on October 21, 2010 at 8:20 pm By:

theheartorg Shelley Wood Cardiology

Vanderbilt now also routinely gene testing for clopidogrel metabolizer status: But the medical center has gone one... http://bit.ly/d827gX

2 years ago...

COGENT Published: Lead Investigator Says He'll Use a PPI in Patients on Dual Antiplatelet Therapy - QualityPoint Technologies

qualitypointtech.net — “Patients on dual antiplatelet therapy had a significant reduction in GI events with omeprazole and no increase in cardiovascular events in the first randomized trial of PPI use with clopidogrel. And a new mechanistic study suggests that the clopidogrel-omeprazole interaction may be dose dependent. HeartwireView full resource at qualitypointtech.net

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Most Recently Shared on October 7, 2010 at 11:36 pm By:

MedicalFeed MedicalFeed Health News Feed

COGENT Published: Lead Investigator Says He'll Use a PPI in Patients on Dual Antiplatelet Therapy: Patients on du... http://bit.ly/diVT5k

2 years ago...

Medical News: PPI Gives Big Protection in Dual Antiplatelet Tx - in Cardiovascular, PCI from MedPage Today

medpagetoday.com — “A pill that combines omeprazole and clopidogrel as part of a dual antiplatelet regimen significantly reduced the risk of gastrointestinal bleeding or other adverse events compared with standard therapView full resource at medpagetoday.com

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Most Recently Shared on October 7, 2010 at 1:27 am By:

MedicalNews Medical News Health News

PPI Gives Big Protection in Dual Antiplatelet Tx (CME/CE) http://ow.ly/19k6RF

2 years ago...

PPI Gives Big Protection in Dual Antiplatelet Tx (CME/CE) - QualityPoint Technologies

qualitypointtech.net — “(MedPage Today) -- A pill that combines omeprazole and clopidogrel as part of a dual antiplatelet regimen significantly reduced the risk of gastrointestinal bleeding or other adverse events compared with standard therapy, researchers reported.View full resource at qualitypointtech.net

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Most Recently Shared on October 6, 2010 at 10:00 pm By:

MedicalFeed MedicalFeed Health News Feed

PPI Gives Big Protection in Dual Antiplatelet Tx (CME/CE): (MedPage Today) -- A pill that combines omeprazole and ... http://bit.ly/aOrEGk

2 years ago...

Symposier - ESC Congress 2010 by topic: from genes to CV outcomes

symposier.com — “Uploaded and shared in Youtube by: escardiodotorg " ESC 2010 Congress Spotlight by Fausto Pinto, CPC Chairman Impact of genotype on outcomes in the CURE ACTIVE study (Efficacy and Safety of Clopidogrel compared with Placebo according to CYP2C19 Genotype in over 6000 patients with Non-ST-elevation Acute Coronary Syndromes and atrial fibrillation) (Guillaume Par, Hamilton) Genetic profiling: ready for clinical use? (Gilles Montalescot, Paris) Genetic determinants of treatment benefit of ACE-inhibiView full resource at symposier.com

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Most Recently Shared on September 27, 2010 at 10:58 pm By:

SympoCardiology Symposier Cardiology Cardiology and Health Business

ESC Congress 2010 by topic: from genes to CV outcomes. http://bit.ly/ccYuWW

2 years ago...

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