Clopidogrel gene and stent thrombosis

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Clopidogrel gene and stent thrombosis

theheart.org

A polymorphism in one of the genes responsible for metabolizing clopidogrel to its active form has been shown to be associated with an increased risk of stent thrombosis in patients undergoing PCI. (Sibbing D et al. Eur Heart J; published online before print February 4, 2009.)

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Tags: Heart, Genes, Anti-Clotting Medication, Plavix, Iscover

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Most Recently Shared on February 12, 2009 at 11:36 pm By:

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Clopidogrel gene mutation linked to higher rate of stent thrombosis http://tinyurl.com/cxm6jp

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MedWire News - Thrombosis - Early stent thrombosis predictors identified

medwire-news.md — “MedWire News Variants in three genes associated with clopidogrel metabolism and platelet receptor function are independently associated with early stent thrombosis in patients undergoing percutaneous coronary intervention, study data show. MedWire NewsView full resource at medwire-news.md

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Subacute Stent Thrombosis Owing to Complete Clopidogrel Resistance Successfully Managed with Prasugrel | Journal of Invasive Cardiology

invasivecardiology.com — “Subacute Stent Thrombosis Owing to Complete Clopidogrel Resistance Successfully Managed with Prasugrel | Journal of Invasive CardiologyView full resource at invasivecardiology.com

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Study examines outcomes of high-dose antiplatelet drug after stent placement

physorg.com — “Modifying a patient's dosage of the antiplatelet drug clopidogrel for 6 months depending on the patient's level of platelet reactivity did not result in combined lower rates of nonfatal heart attack, stent thrombosis (clot) and cardiovascular death in patients who had a procedure such as balloon angioplasty ...View full resource at physorg.com

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newswise.com — “Modifying a patient--™s dosage of the antiplatelet drug clopidogrel for 6 months depending on the patient--™s level of platelet reactivity did not result in combined lower rates of nonfatal heart attack, stent thrombosis (clot) and cardiovascular death in patients who had a procedure such as balloon angioplasty and received a drug-releasing coronary stent, according to a study in the March 16 issue of JAMA.View full resource at newswise.com

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Study Examines Outcomes of High-Dose Antiplatelet Drug After Stent Placement: Modifying a patient's dosage of th... http://bit.ly/hOcHHY

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newswise.com — “Modifying a patient--™s dosage of the antiplatelet drug clopidogrel for 6 months depending on the patient--™s level of platelet reactivity did not result in combined lower rates of nonfatal heart attack, stent thrombosis (clot) and cardiovascular death in patients who had a procedure such as balloon angioplasty and received a drug-releasing coronary stent, according to a study in the March 16 issue of JAMA.View full resource at newswise.com

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drugs.com — “People with certain gene variants who take the blood-thinning drug Plavix (clopidogrel) may be at increased risk for serious complications after coronary stentView full resource at drugs.com

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theheart.org — “A platelet-reactivity index of over 60% on the VASP test was associated with an increased rate of death and stent thrombosis. The deleterious impact of a low response to clopidogrel was significantly higher in patients who received a drug-eluting stent.View full resource at theheart.org

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theheart.org — “Another retrospective analysis, this time in stented patients, shows no significant increases in risk of death, ACS, or stent thrombosis in patients taking concomitant proton-pump inhibitors, mostly pantoprazole. But one expert says no conclusions can be made until the FDA reveals the data it used to decide that a warning was warranted.View full resource at theheart.org

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PPIs, clopidogrel, and stent implantation: No risk? FDA data coming soon: Another retrospective analysis, this tim... http://bit.ly/akQLR8

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Cardiology Medical News about Clopidogrel

mdlinx.com — “High Maintenance Dosage of Clopidogrel is Associated with a Reduced Risk of Stent Thrombosis in Clopidogrel-Resistant PatientsView full resource at mdlinx.com

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Most Recently Shared on February 11, 2010 at 12:55 pm By:

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