BMC Medicine | Abstract | Insufficient maintenance DNA methylation is associated with abnormal embryonic development

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BMC Medicine | Abstract | Insufficient maintenance DNA methylation is associated with abnormal embryonic development

Early pregnancy loss (EPL) is a frustrating clinical problem, whose mechanisms are not completely understood. DNA methylation, which includes maintenance methylation and de novo methylation directed by DNA methyltransferases (DNMTs), is important for embryo development. Abnormal function of these DNMTs may have serious consequences for embryonic development.

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Tags: Drug, Pregnancy, Medical, Medicine