Recommended Pages at arthritis-research.com

Arthritis Research & Therapy | Abstract | Thrombin induces heme oxygenase-1 expression in human synovial fibroblasts through protease-activated receptor signaling pathways

arthritis-research.com — “Thrombin is a key factor in the stimulation of fibrin deposition, angiogenesis, and proinflammatory processes. Abnormalities in these processes are primary features of osteoarthritis (OA). Heme oxygenase (HO)-1 is a stress-inducible rate-limiting enzyme in heme degradation that confers cytoprotection against oxidative injury. Here, we investigated the intracellular signaling pathways involved in thrombin-induced HO-1 expression in human synovial fibroblasts (SF).View full resource at arthritis-research.com

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Most Recently Shared on April 27, 2012 at 6:01 pm By:

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Thrombin induces heme oxygenase-1 expression in human synovial fibroblasts through protease-activated receptor s... http://t.co/QQEywvA5

1 month ago...

Arthritis Research & Therapy | Abstract | Risk of end-stage renal disease associated with gout: a nationwide population study

arthritis-research.com — “We explored the risk of end-stage renal disease (ESRD) among gout patients in a representative cohort in Taiwan.View full resource at arthritis-research.com

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Most Recently Shared on April 18, 2012 at 8:59 pm By:

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Risk of end-stage renal disease associated with gout: a nationwide population study: Conclusions: Gout is associ... http://t.co/9wFpGICa

1 month ago...

Arthritis Research & Therapy | Abstract | Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: a cross-sectional study

arthritis-research.com — “Reported findings on the relationship between adiposity and atherosclerotic cardiovascular disease (ACVD) risk in rheumatoid arthritis (RA) are contradictory and originate in developed populations. Approximately 80% of ACVD now occurs in developing countries. We aimed to ascertain the associations of clinical obesity measures with metabolic cardiovascular risk and atherosclerosis in African women with RA from a developing black and developed Caucasian population.View full resource at arthritis-research.com

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Most Recently Shared on March 20, 2012 at 7:35 am By:

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Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: ... http://t.co/Kp8io1fo

2 months ago...

Arthritis Research & Therapy | Abstract | Effect of pregnancy on serum cytokines in SLE patients

arthritis-research.com — “To evaluate an extensive panel of cytokines involved in immune regulation during pregnancy in patients with systemic lupus erythematosus (SLE) and in healthy women.View full resource at arthritis-research.com

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Most Recently Shared on March 16, 2012 at 4:35 pm By:

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RT @hil4r1: Th1/Th2 ratio protects women with lupus (SLE) against ‘flare ups’ during pregnancy http://t.co/7ijjftKx @BioMedCentral #SLE

2 months ago...

Arthritis Research & Therapy | Abstract | Functional role of IL-22 in psoriatic arthritis

arthritis-research.com — “Interleukin-22 (IL-22) is a cytokine of IL-10 family with significant proliferative effect on different cell lines. Immunopathological role of IL-22 has been studied in rheumatoid arthritis (RA) and psoriasis. Here we are reporting the functional role of IL-22 in the inflammatory and proliferative cascades of psoriatic arthritis (PsA).View full resource at arthritis-research.com

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Most Recently Shared on March 16, 2012 at 12:34 am By:

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Functional role of IL-22 in psoriatic arthritis: Conclusion: SF of PsA patients have higher concentration of IL-... http://t.co/AuIomrKy

2 months ago...

Arthritis Research & Therapy | Abstract | Clinical Features of Symptomatic Patellofemoral Joint Osteoarthritis

arthritis-research.com — “Patellofemoral joint osteoarthritis (OA) is common and leads to pain and disability. However, current classification criteria do not distinguish between patellofemoral and tibiofemoral joint OA. The objective of this study was to provide empirical evidence of the clinical features of patellofemoral joint OA (PFJOA) and to explore the potential for making a confident clinical diagnosis in the community setting.View full resource at arthritis-research.com

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Most Recently Shared on March 16, 2012 at 12:34 am By:

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Clinical Features of Symptomatic Patellofemoral Joint Osteoarthritis: Conclusions: Early isolated PFJOA is clini... http://t.co/jIMrwGBk

2 months ago...

Arthritis Research & Therapy | Abstract | Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators?

arthritis-research.com — “We have taken advantage of the large screening capacity of a multiplex immunoassay to better define the respective contribution of articular versus systemic cytokines in experimental arthritis.View full resource at arthritis-research.com

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Most Recently Shared on March 15, 2012 at 11:50 am By:

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Arthritis Research & Therapy | Abstract | Cytokines profiling by ... http://t.co/tAiFwPZe

3 months ago...

Arthritis Research & Therapy | Full text | Plasma proteins take their toll on the joint in osteoarthritis

arthritis-research.com — “In their recent study, Sohn and colleagues identify multiple plasma proteins in the synovial fluid of patients with osteoarthritis (OA) and demonstrate the capacity of several of the proteins to activate macrophages via the innate immune receptor Toll-like receptor-4 (TLR-4). The authors speculate that the plasma proteins transit into the synovial compartment at sites of tissue damage where the endothelial barrier may be compromised, thus bringing them into contact with the articular surface andView full resource at arthritis-research.com

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Most Recently Shared on March 6, 2012 at 5:48 am By:

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Plasma proteins take their toll on the joint in osteoarthritis: see editorial (Source: Arthritis Research and Therapy) http://t.co/pYNSfD4z

3 months ago...

Arthritis Research & Therapy | Abstract | Can anti-cyclic citrullinated peptide antibody negative RA be subdivided into clinical subphenotypes?

arthritis-research.com — “Studies investigating genetic risk factors for susceptibility to rheumatoid arthritis (RA) studied anti-citrullinated peptide antibody (CCP)-positive RA more frequently than anti-CCP-negative RA. One of the reasons for this is the perception that anti-CCP negative RA may include patients that fulfilled criteria for RA but belong to a wide range of diagnoses. We aimed to evaluate the validity of this notion and explored whether clinical subphenotypes can be discerned within anti-CCP-negative RA.View full resource at arthritis-research.com

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Most Recently Shared on October 27, 2011 at 7:58 pm By:

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Can anti-cyclic citrullinated peptide antibody negative RA be subdivided into clinical subphenotypes?: Conclusio... http://t.co/6zh4gfhm

7 months ago...

Arthritis Research & Therapy | Full text | Green tea: a new option for the prevention or control of osteoarthritis

arthritis-research.com — “IL-1? is a major cytokine driving the inflammatory processes leading to the pathophysiology of osteoarthritis and other inflammatory diseases. Blockade of IL-1? activity using substances such as the naturally occurring IL-1 receptor antagonist or anti-IL-1? monoclonal antibody are currently being used or tested as therapy. However, such treatments are ineffective in osteoarthritis. In a recent study, epigallocatechin-3-gallate, a green tea polyphenol, was found to be effective in reducing IL-1?-View full resource at arthritis-research.com

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Most Recently Shared on August 11, 2011 at 12:59 am By:

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Green tea: a new option for the prevention or control of osteoarthritis: ${item.shortDescription} (Source: BioMe... http://bit.ly/nLJRTS

10 months ago...

Arthritis Research & Therapy | Abstract | Postural control deficits in people with fibromyalgia: a pilot study

arthritis-research.com — “Postural instability and falls are increasingly recognized problems in fibromyalgia (FM). The purpose of this study was to determine if FM patients, compared to age-matched controls, had differences in dynamic posturography, including sensory, motor, and limits of stability. We further sought to determine if postural instability was associated with strength, proprioception and lower extremity myofascial trigger points (MTPs), FM symptoms and physical function, dyscognition, balance confidence anView full resource at arthritis-research.com

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Most Recently Shared on August 4, 2011 at 3:38 pm By:

GinaSelir Gina Selir Patient Expert

Postural control deficits in people with fibromyalgia: a pilot study http://bit.ly/pxSr7g

10 months ago...

TXNDC5 is upregulated in synovial tissue of RA patients & has #genetic effect on the risk of RA & AS. #rheum #research http://bit.ly/o9bI8L

arthritis-research.com — “TXNDC5 is upregulated in synovial tissue of RA patients & has #genetic effect on the risk of RA & AS. #rheum #research http://bit.ly/o9bI8LView full resource at arthritis-research.com

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Most Recently Shared on July 30, 2011 at 2:28 pm By:

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TXNDC5 is upregulated in synovial tissue of RA patients & has #genetic effect on the risk of RA & AS. #rheum #research http://bit.ly/o9bI8L

10 months ago...

Arthritis Research & Therapy | Abstract | Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development

arthritis-research.com — “Collagen-induced arthritis (CIA) is a mouse model for rheumatoid arthritis (RA) and is induced after immunization with type II collagen (CII). CIA, like RA, is an autoimmune disease leading to destruction of cartilage and joints, and both the priming and inflammatory phases have been suggested to be dependent on proteases. In particular, the cysteine proteases have been proposed to be detrimental to the arthritic process and even immunomodulatory. A natural inhibitor of cysteine proteases is cysView full resource at arthritis-research.com

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Most Recently Shared on March 29, 2011 at 1:32 am By:

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Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chro... http://bit.ly/gvJSIe

1 year ago...

Arthritis Research & Therapy | Abstract | Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine

arthritis-research.com — “Glucosamine is an amino-monosaccharide and precursor of glycosaminoglycans, major components of the joint cartilage. Glucosamine has been clinically introduced for the treatment of osteoarthritis but the data about its protective role in disease are insufficient. The goal of this study was to investigate the effect of long term administration of glucosamine on bone resorption and remodeling.View full resource at arthritis-research.com

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Most Recently Shared on March 17, 2011 at 2:14 am By:

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Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine:... http://bit.ly/hsRgUa

1 year ago...

Abstract | Nordic walking in fibromyalgia: a means of promoting fitness that is easy for busy clinicians to recommend

arthritis-research.com — “Abstract | Nordic walking in fibromyalgia: a means of promoting fitness that is easy for busy clinicians to recommendView full resource at arthritis-research.com

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Most Recently Shared on February 17, 2011 at 11:17 pm By:

GinaSelir Gina Selir Patient Expert

Nordic walking in fibromyalgia: a means of promoting fitness that is easy for busy clinicians to recommend http://bit.ly/eYS7QU

1 year ago...

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