Arthritis Research & Therapy | Abstract | Can anti-cyclic citrullinated peptide antibody negative RA be subdivided into clinical subphenotypes?

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Arthritis Research & Therapy | Abstract | Can anti-cyclic citrullinated peptide antibody negative RA be subdivided into clinical subphenotypes?

arthritis-research.com

Studies investigating genetic risk factors for susceptibility to rheumatoid arthritis (RA) studied anti-citrullinated peptide antibody (CCP)-positive RA more frequently than anti-CCP-negative RA. One of the reasons for this is the perception that anti-CCP negative RA may include patients that fulfilled criteria for RA but belong to a wide range of diagnoses. We aimed to evaluate the validity of this notion and explored whether clinical subphenotypes can be discerned within anti-CCP-negative RA.

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Tags: Genetic, Arthritis, Rheumatoid Arthritis

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