ArmaGen® Re-engineers Erythropoietin For Brain Penetration

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ArmaGen® Re-engineers Erythropoietin For Brain Penetration

Human erythropoietin (EPO) is a potent neuroprotective agent for multiple brain disorders, including stroke, brain and spinal cord injury, and Parkinson's disease. However, EPO drug development fo

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Tags: Anemia Medication, Neurology, Brain, Procrit, Eprex, Epogen, NeoRecormon, Epogin

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ArmaGen uses BBB molecular Trojan horse platform technology to create brain penetrating form of human EPO

news-medical.net — “Human erythropoietin (EPO) is a potent neuroprotective agent for multiple brain disorders, including stroke, brain and spinal cord injury, and Parkinson's disease. However, EPO drug development for the brain is limited, because EPO does not cross the blood-brain barrier (BBB). In acute stroke or brain injury, the BBB is intact in the early hours after the insult when neuroprotection is still possible. Therefore, large molecule biopharmaceuticals such as EPO must be re-engineered to enable BBB tr” View full resource at news-medical.net