Animal Models Related to Congenital Heart Disease and Clinical Research in Pulmonary Hypertension

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Animal Models Related to Congenital Heart Disease and Clinical Research in Pulmonary Hypertension

There are several animal models for studying human pulmonary hypertension (PH). An increased flow model in pigs was developed at the University Hospital in Heidelberg in order to simulate congenital heart disease. The high pulmonary blood flow is achieved by installation of a Blalock-Taussig anastomosis. In order to further improve this model by adding a pressure component, the left pulmonary artery is ligated. An acute model, which is used at the Innsbruck Medical University, addresses another

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Tags: Heart, Heart Disease, Coronary Artery Disease, Congenital Heart Defect, Disease and Condition, Pulmonology, disease, Nature