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Written by the OrganizedWisdom Team with as the reviewer. All original content is supervised by the The OrganizedWisdom Medical Review Team
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The specific cause of ankylosing spondylitis is unknown, but genetic factors seem to play a role.About 95% of people who have ankylosing spondylitis also have a genetic marker known as human leukocyte antigen-B27 (HLA-B27).About eight people in 100 among American Caucasians are born with the HLA-B27 gene. The gene is much less common among African Americans.
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