Pyrimidine
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New pyrimidine compounds may lead to improved treatments for childhood brain cancer
sciencedaily.com — “Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. A recent study shows that pyrazolo-[3,4-d]--pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and causing cancer cell death in medulloblastoma.” View full resource at sciencedaily.com
Most Recently Shared on April 6, 2010 at 3:30 pm By:
New pyrimidine compounds may lead to improved treatments for childhood brain cancer: Src (short for sarcoma) is a ... http://bit.ly/cDVYOE
New pyrimidine compounds may lead to improved treatments for childhood brain cancer
physorg.com — “Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.” View full resource at physorg.com
Most Recently Shared on April 6, 2010 at 7:10 pm By:
New pyrimidine compounds may lead to improved treatments for childhood brain cancer http://tw.physorg.com/189782701
Synthesis of substituted thieno[2,3-d]pyrimidine-2... [Eur J Med Chem. 2010] - PubMed result
ncbi.nlm.nih.gov — “PubMed is a service of the U.S. National Library of Medicine that includes over 19 million citations from MEDLINE and other life science journals for biomedical articles back to the 1950s. PubMed includes links to full text articles and other related resources.” View full resource at ncbi.nlm.nih.gov
Most Recently Shared on August 11, 2010 at 5:04 pm By:
Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antivi... http://bit.ly/btHum3
Fluorouracil Toxicity and DPYD: eMedicine Genomic Medicine
emedicine.medscape.com — “Overview: 5-Fluorouracil (5FU) is a fluorinated pyrimidine analogue commonly used in combination chemotherapy regimens for patients with breast, colorectal, lung, and other malignancies. Dihydropyrimidine dehydrogenase (DPD), an enzyme encoded by the DPYD gene, is the rate-limiting ...” View full resource at emedicine.medscape.com
Most Recently Shared on June 2, 2010 at 7:58 pm By:
Patients with known or suspected DPD deficiency are generally advised to avoid therapy with 5FU/capecitabine. Learn why.http://bit.ly/bclkvC
Evaluation of the in vitro antiretroviral potenti... [Acta Virol. 2012] - PubMed - NCBI
ncbi.nlm.nih.gov — “PubMed comprises more than 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.” View full resource at ncbi.nlm.nih.gov
Most Recently Shared on March 18, 2012 at 7:50 am By:
Evaluation of the in vitro antiretroviral potential of some Biginelli-type pyrimidines.: Authors: Zabihollahi R,... http://t.co/a79a6yEe
Fluorouracil IV --(5-FU, Adrucil) - ONA
oncologynurseadvisor.com — “Fluorouracil, a pyrimidine antagonist, is an antimetabolite antineoplastic agent indicated for colorectal, gastric, metastatic breast, metastatic colorectal, and pancreatic cancers.” View full resource at oncologynurseadvisor.com
Most Recently Shared on March 17, 2011 at 9:09 pm By:
NASA Reproduces A Building Block Of Life In Laboratory
feeds.sciencedaily.com — “NASA scientists studying the origin of life have reproduced uracil, a key component of our hereditary material, in the laboratory. They discovered that an ice sample containing pyrimidine exposed to ultraviolet radiation under space-like conditions produces this essential ingredient of life.” View full resource at feeds.sciencedaily.com
Most Recently Shared on November 10, 2009 at 1:13 pm By:
NASA Reproduces A Building Block Of Life In Laboratory: NASA scientists studying the origin of life have reproduced ... http://bit.ly/2Yhsw4
Exome sequencing identifies the cause of a mendelian disorder : Nature Genetics : Nature Publishing Group
nature.com — “Michael Bamshad, Jay Shendure and colleagues report the first application of exome resequencing to identify the cause of a mendelian disorder. They sequenced the exomes of four individuals with Miller syndrome in three independent families and identify mutations in DHODH, a key enzyme in the pyrimidine de novo biosynthesis pathway, as causal for the disorder.” View full resource at nature.com
Most Recently Shared on November 14, 2009 at 3:54 am By:
Exome sequencing identifies the cause of a mendelian disorder http://bit.ly/VHZBg
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