Pyrimidine

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New pyrimidine compounds may lead to improved treatments for childhood brain cancer

sciencedaily.com — “Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. A recent study shows that pyrazolo-[3,4-d]--pyrimidine-derivatives, designed to target Src, may be effective in interfering with the cell cycle and causing cancer cell death in medulloblastoma.View full resource at sciencedaily.com

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Most Recently Shared on April 6, 2010 at 3:30 pm By:

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New pyrimidine compounds may lead to improved treatments for childhood brain cancer: Src (short for sarcoma) is a ... http://bit.ly/cDVYOE

2 years ago...

New pyrimidine compounds may lead to improved treatments for childhood brain cancer

physorg.com — “Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.View full resource at physorg.com

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Most Recently Shared on April 6, 2010 at 7:10 pm By:

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New pyrimidine compounds may lead to improved treatments for childhood brain cancer http://tw.physorg.com/189782701

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Synthesis of substituted thieno[2,3-d]pyrimidine-2... [Eur J Med Chem. 2010] - PubMed result

ncbi.nlm.nih.gov — “PubMed is a service of the U.S. National Library of Medicine that includes over 19 million citations from MEDLINE and other life science journals for biomedical articles back to the 1950s. PubMed includes links to full text articles and other related resources.View full resource at ncbi.nlm.nih.gov

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Most Recently Shared on August 11, 2010 at 5:04 pm By:

HIV_Wisdom OrganizedWisdom HIV OW Health

Synthesis of substituted thieno[2,3-d]pyrimidine-2,4-dithiones and their S-glycoside analogues as potential antivi... http://bit.ly/btHum3

2 years ago...

Fluorouracil Toxicity and DPYD: eMedicine Genomic Medicine

emedicine.medscape.com — “Overview: 5-Fluorouracil (5FU) is a fluorinated pyrimidine analogue commonly used in combination chemotherapy regimens for patients with breast, colorectal, lung, and other malignancies. Dihydropyrimidine dehydrogenase (DPD), an enzyme encoded by the DPYD gene, is the rate-limiting ...View full resource at emedicine.medscape.com

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Most Recently Shared on June 2, 2010 at 7:58 pm By:

SusanS_Health Susan Scroggins Active Health Library and Health Advocate

Patients with known or suspected DPD deficiency are generally advised to avoid therapy with 5FU/capecitabine. Learn why.http://bit.ly/bclkvC

2 years ago...

Evaluation of the in vitro antiretroviral potenti... [Acta Virol. 2012] - PubMed - NCBI

ncbi.nlm.nih.gov — “PubMed comprises more than 21 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.View full resource at ncbi.nlm.nih.gov

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Most Recently Shared on March 18, 2012 at 7:50 am By:

HIV_Wisdom OrganizedWisdom HIV OW Health

Evaluation of the in vitro antiretroviral potential of some Biginelli-type pyrimidines.: Authors: Zabihollahi R,... http://t.co/a79a6yEe

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Fluorouracil IV --(5-FU, Adrucil) - ONA

oncologynurseadvisor.com — “Fluorouracil, a pyrimidine antagonist, is an antimetabolite antineoplastic agent indicated for colorectal, gastric, metastatic breast, metastatic colorectal, and pancreatic cancers.View full resource at oncologynurseadvisor.com

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Most Recently Shared on March 17, 2011 at 9:09 pm By:

NASA Reproduces A Building Block Of Life In Laboratory

feeds.sciencedaily.com — “NASA scientists studying the origin of life have reproduced uracil, a key component of our hereditary material, in the laboratory. They discovered that an ice sample containing pyrimidine exposed to ultraviolet radiation under space-like conditions produces this essential ingredient of life.View full resource at feeds.sciencedaily.com

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Most Recently Shared on November 10, 2009 at 1:13 pm By:

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NASA Reproduces A Building Block Of Life In Laboratory: NASA scientists studying the origin of life have reproduced ... http://bit.ly/2Yhsw4

3 years ago...

Exome sequencing identifies the cause of a mendelian disorder : Nature Genetics : Nature Publishing Group

nature.com — “Michael Bamshad, Jay Shendure and colleagues report the first application of exome resequencing to identify the cause of a mendelian disorder. They sequenced the exomes of four individuals with Miller syndrome in three independent families and identify mutations in DHODH, a key enzyme in the pyrimidine de novo biosynthesis pathway, as causal for the disorder.View full resource at nature.com

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Most Recently Shared on November 14, 2009 at 3:54 am By:

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