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Hurler's Syndrome - Synonym: Mucopolysaccharidosis Type IH The mucopolysaccharidoses are a group of inherited disorders caused by a lack of specific lysosomal enzymes involved in the degradation of glycosaminoglycans. Deficiency of alpha-L-iduronidase can result in a wide range of phenotypes including Hurler (severe), Scheie (mild) and Hurler-Scheie (intermediate) syndromes.1
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