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Written by the OrganizedWisdom Team with as the reviewer. All original content is supervised by the The OrganizedWisdom Medical Review Team

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Influenza pandemics have occurred every 10 to 60 years, with three occurring in the twentieth century (1918, 1957-1958, and 1967-1968). Influenza pandemics occur when there is a notable genetic change (termed genetic shift) in the circulating strain of influenza. Because of this genetic shift, a large portion of the human population is entirely vulnerable to infection from the new pandemic strain.

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