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Familial Polyposis of the Colon (Gardner's Syndrome) - Synonyms: familial adenomatous polyposis (FAP), familial polyposis coli Widespread development of adenomas in the colon and rectum. Gardner described the occurrence of familial adenomatous polyposis with the extracolonic manifestations of desmoids, osteomas, and epidermoid cysts in 1951. The number of polyps can range from no detectable polyps at colonoscopy to more than 7000 seen on resected specimens of bowel. The polyposis predominantly affects the left colon (80-90%).1
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