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Diagnosis of NDI Nephrogenic diabetes insipidus (NDI) is only one of four types of diabetes insipidus (DI), for which all patients exhibit extreme thirst (polydipsia) and excessive urination (polyuria) as symptoms. Distinguishing among the different types of DI can be straightforward under some conditions, and under other conditions requires additional tests. Factors taken into consideration during diagnosis include: urinary concentration (Urine contains both a solute aspect - salts, minerals, sugars, and a solvent aspect - the body water minus the solutes. Urine concentration is measured in terms of the ratio of osmotically active particles to body water.), plasma concentration (the ratio of plasma solutes to plasma solvent),

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