Chronic Myeloid Leukemia

A brief digest about this topic

Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, however, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work. In chronic myeloid leukemia (CML), there are too many of a specific type of white blood cell called a granulocyte.

Sometimes CML does not cause any symptoms at all. If you have symptoms, they may include:

  • Feeling very tired
  • Weight loss
  • Night sweats
  • Fever
  • Pain or a feeling of fullness below the ribs on the left side

Tests that examine the blood and bone marrow diagnose CML. Treatments include chemotherapy, radiation therapy, stem cell transplants, infusion of donated white blood cells following stem cell transplants, immune therapy, or surgery to remove the spleen.

NIH: National Cancer Institute

Provided by: NIH - National Institute of Health

Links shared publicly online about this topic

Chronic Myeloid Leukemia: New Approaches Needed

medicalnewstoday.com — “Chronic myeloid leukemia (CML) was transformed from a fatal disease to a chronic condition by the development of a drug known as imatinib, which targets the protein that drives this disease (BCR-AView full resource at medicalnewstoday.com

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Most Recently Shared on December 15, 2010 at 1:05 pm By:

Medicine and Technology [part of HCPLive]: Optimal treatment for CML (Chronic Myeloid Leukemia)

medicineandtechnology.com — “Medicine and Technology [part of HCPLive]: Optimal treatment for CML (Chronic Myeloid Leukemia)View full resource at medicineandtechnology.com

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Most Recently Shared on June 7, 2010 at 1:50 pm By:

DrJosephKim Joseph Kim, MD, MPH Doctor and Physician

Optimal treatment for CML (Chronic Myeloid Leukemia) http://bit.ly/bM5HtV

2 years ago...

Chronic Myeloid Leukemia: New Lab Test Could Identify Imatinib Resistance

medicalnewstoday.com — “Scientists in Japan may have developed a way to accurately predict those patients who will resist treatment with imatinib, which is the standard of care for chronic myeloid leukemia (CML).View full resource at medicalnewstoday.com

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Most Recently Shared on July 29, 2010 at 3:07 pm By:

mnt_leukemia MNT Leukemia Health News

Chronic Myeloid Leukemia: New Lab Test Could Identify Imatinib Resistance http://mnt.to/3GJC #lymphoma #leukemia

2 years ago...

NICE Recommends Nilotinib for Chronic Myeloid Leukemia - OncologySTAT

oncologystat.com — “NICE Recommends Nilotinib for Chronic Myeloid Leukemia - Elsevier Global Medical News. 2011 Aug 17, J SmithView full resource at oncologystat.com

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Most Recently Shared on August 23, 2011 at 9:56 pm By:

jangeissler Jan Geissler Health Advocate

Price cut makes NICE withdraw their negative 'cost effectiveness' appraisal of Nilotinib in 2nd line CML treatment in UK http://ow.ly/6aXXN

9 months ago...

Imatinib for Chronic Myeloid Leukemia: The Impact of Its Effectiveness and Long-term Side Effects

jnci.oxfordjournals.org — “Imatinib for Chronic Myeloid Leukemia: The Impact of Its Effectiveness and Long-term Side EffectsView full resource at jnci.oxfordjournals.org

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Most Recently Shared on March 24, 2011 at 9:40 am By:

Chronic Myeloid Leukemia: Second-Line Drug Evokes Faster Response, Fewer Side Effects, Pivotal Study Finds

medicalnewstoday.com — “Dasatanib, a medication currently approved as treatment for drug-resistant chronic myeloid leukemia (CML), provided patients with quicker, better responses as a first therapy than the existing froView full resource at medicalnewstoday.com

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Most Recently Shared on June 7, 2010 at 12:06 pm By:

mnt_leukemia MNT Leukemia Health News

Chronic Myeloid Leukemia: Second-Line Drug Evokes Faster Response, Fewer Side Effects, Pivotal Study Finds http://mnt.to/3Dz6

2 years ago...

Molecular Cancer | Abstract | RhoA: A therapeutic target for chronic myeloid leukemia

molecular-cancer.com — “Chronic Myeloid Leukemia (CML) is a malignant pluripotent stem cells disorder of myeloid cells. In CML patients, polymorphonuclear leukocytes (PMNL) the terminally differentiated cells of myeloid series exhibit defects in several actin dependent functions such as adhesion, motility, chemotaxis, agglutination, phagocytosis and microbicidal activities. A definite and global abnormality was observed in stimulation of actin polymerization in CML PMNL. Signalling molecules ras and rhoGTPases regulateView full resource at molecular-cancer.com

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Most Recently Shared on March 26, 2012 at 12:30 pm By:

Faces of Chronic Myeloid Leukemia: Perspectives from all across the world - CML Advocates Network

cmladvocates.net — “Global network of patient groups supporting patients with Chronic Myeloid Leukemia (CML), connecting more than 50 groups in more than 40 countries on all continentsView full resource at cmladvocates.net

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Most Recently Shared on September 12, 2011 at 3:52 pm By:

jangeissler Jan Geissler Health Advocate

CML has different faces! See the 98 photos here - more coming in day by day! http://ow.ly/6s0u8

8 months ago...

Oncology Article | Front-Line Therapy With Second-Generation Tyrosine Kinase Inhibitors in Patients With Early Chronic Phase Chronic Myeloid Leukemia: What Is the Optimal Response

mdlinx.com — “Front-Line Therapy With Second-Generation Tyrosine Kinase Inhibitors in Patients With Early Chronic Phase Chronic Myeloid Leukemia: What Is the Optimal ResponseView full resource at mdlinx.com

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Most Recently Shared on October 14, 2011 at 7:42 am By:

MDLinx Sandeep Pulim MD Doctor, Health Communicator, and Physician

Front-Line Therapy With Second-Generation Tyrosine Kinase Inhibitors in Patients With Early Chronic Ph... http://t.co/QcxBed17 #oncology

7 months ago...

Chronic myeloid leukemia: New lab test could identify imatinib resistance Scientists in Japan may have developed a way .. http://dld.bz/rJBG

sciencedaily.com — “Chronic myeloid leukemia: New lab test could identify imatinib resistance Scientists in Japan may have developed a way .. http://dld.bz/rJBGView full resource at sciencedaily.com

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Most Recently Shared on August 13, 2010 at 4:07 pm By:

medical_tweets medical_tweets Health News

Chronic myeloid leukemia: New lab test could identify imatinib resistance Scientists in Japan may have developed a way .. http://dld.bz/rJBG

2 years ago...

Chronic myeloid leukemia: New lab test could identify imatinib resistance: Scientists in Japan may have developed ... http://bit.ly/c3YmnM

sciencedaily.com — “Chronic myeloid leukemia: New lab test could identify imatinib resistance: Scientists in Japan may have developed ... http://bit.ly/c3YmnMView full resource at sciencedaily.com

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Most Recently Shared on July 29, 2010 at 2:21 pm By:

sciencedaily sciencedaily Health News

Chronic myeloid leukemia: New lab test could identify imatinib resistance: Scientists in Japan may have developed ... http://bit.ly/c3YmnM

2 years ago...

Oncology Medical Article | Targeting of GSK3β promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors preserving normal stem cells

mdlinx.com — “Oncology Medical Article: Targeting of GSK3β promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors preserving normal stem cellsView full resource at mdlinx.com

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Most Recently Shared on January 27, 2012 at 3:21 pm By:

MDLinx Sandeep Pulim MD Doctor, Health Communicator, and Physician

Targeting of GSK3β promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukem... http://t.co/4k91cms0 #oncology

4 months ago...

Assessment of BCR-ABL1 Transcript Levels at 3 Months Is the Only Requirement for Predicting Outcome for Patients With Chronic Myeloid Leukemia Treated With Tyrosine Kinase Inhibitors

jco.ascopubs.org — “Assessment of BCR-ABL1 Transcript Levels at 3 Months Is the Only Requirement for Predicting Outcome for Patients With Chronic Myeloid Leukemia Treated With Tyrosine Kinase InhibitorsView full resource at jco.ascopubs.org

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Most Recently Shared on January 30, 2012 at 7:14 pm By:

garciamanero G Garcia-Manero Internist, Oncologist, Physician, and Doctor

Molecular response at 3 months may be best predictor of outocme in CML... http://t.co/GE5GewX7

4 months ago...

Leukemia, Myeloid Leukemia, Myeloid, Chronic-Phase Stem Cells on #MDlinx

mdlinx.com — “Leukemia, Myeloid Leukemia, Myeloid, Chronic-Phase Stem Cells on #MDlinxView full resource at mdlinx.com

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Most Recently Shared on October 8, 2010 at 6:49 am By:

MDLinx Sandeep Pulim MD Doctor, Health Communicator, and Physician

Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 rece... http://bit.ly/bj5XvL #oncology

2 years ago...

Oncology Article | Leukemia, Myeloid Leukemia, Myeloid, Chronic-Phase

mdlinx.com — “Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase following imatinib resistance or intolerance: 24-month follow-up resultsView full resource at mdlinx.com

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Most Recently Shared on November 29, 2010 at 5:01 pm By:

MDLinx Sandeep Pulim MD Doctor, Health Communicator, and Physician

Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase following imatinib r... http://bit.ly/ewAMpa #oncology

1 year ago...

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  • mnt_leukemia

    MNT Leukemia

    The latest lymphoma and leukemia news published daily. Articles from research centers, universities and prestigious journals.

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  • DrJosephKim

    Joseph Kim, MD, MPH

    Physician, MIT engineer, technology advocate, blogger: MedicineandTechnology.com NonClinicalJobs.com MedicalSmartphones.com MobileHealthComputing.com

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  • mnt_leukemia

    MNT Leukemia

    The latest lymphoma and leukemia news published daily. Articles from research centers, universities and prestigious journals.

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